ichthyosis

Overview
Fish scale psoriasis refers to a condition in which the skin of the whole body becomes dry and scales or dandruff comes off.Some fish scale psoriasis are congenital (genetic), while others are acquired by disease or medicine.There are various types of congenital fish scale psoriasis depending on the gene, symptoms, and affected area (only skin or with systemic symptoms).Genetically mutated genes are usually transmitted from parent to child, but they can occur spontaneously.Inborn psoriasis can occur at birth or in infancy or childhood.cause
Various genetic mutations cause abnormalities in the epidermal cells on the top surface of the skin, and each layer is noticeably thickened.Common fish scale psoriasis, which is the most frequent fish scale psoriasis, is caused by filagrin gene mutation.The second most common X-linked recessive fish scale is caused by abnormalities in steroid sulfatase genes.There are also acquired ones, which are triggered by diseases such as malignant lymphoma, hypothyroidism, AIDS, and other side effects of drugs.symptom
Common fish scale psoriasis is the most frequent, but since there are many minor cases, there are many cases in which the skin is considered dry and cannot be properly diagnosed.It is characterized by the enhancement of the skin crest of the palm of the hand and the tendency to complicate atopic dermatitis.Other congenital fish scale psoriasis are more severe than normal fish scale psoriasis.Many of them develop during the neonatal period from birth, and the surface of the skin is covered with very thick keratin over a wide area of the whole body or body.In addition to the redness of the skin, fish scales and skin, fish scale psoriasis syndrome causes abnormalities in various organs other than the skin.Epidermal lytic fish scale psoriasis is characterized by blisters and blisters.In congenital fish scale-like erythema and clown-like fish scale-like erythema, eyelids and lips are turned over and ears are deformed.Clown-like fish scale psoriasis is particularly severe, and noticeably thick and hard scales can be found throughout the body.While there are cases of death during neonatal and infant stage, there are cases in which symptoms are relieved by the time they reach school childhood.Fish scale psoriasis often lasts for a lifetime.examination and diagnosis
Diagnosis is performed by clinical findings, pathological findings, family history, and genetic analysis.In the case of congenital scaly psoriasis, it is suspected that the skin of infants and infants has a characteristic scaly or skin-like abnormality.A diagnosis is confirmed by cutting the skin small while using a local anesthetic and examining the gene by a skin biopsy for detailed observation under a microscope or a blood test.In the case of fish scale psoriasis syndrome, symptoms are often seen in organs other than the skin, so pediatricians, ophthalmologists and otolaryngologists may examine them.Since acquired fish scale psoriasis develops after taking medicine or developing other diseases, skin biopsy is performed to determine the cause.treatment
Since no cure has been found, symptomatic therapy is the main treatment to relieve symptoms.Moisturizers, vitamin A, and active vitamin D3 ointment are used, and drugs that work on keratin such as Vaseline and urea are used externally.Surgery may be performed for skeletal deformation and contracture of limbs.In severe cases, it is necessary to supplement water with intravenous drip, manage breathing, maintain normal body temperature, and control skin infection.Although management in the neonatal intensive care unit may be required, the survival rate is increasing due to advances in technology.In some cases, retinoid preparations were administered throughout the body from the neonatal stage and were effective.Although rare cases of death have been reported in severe cases, improvement is expected basically by continuing treatment.However, in many cases, lifelong treatment is required.precautions after prevention/treatment
Fish scale psoriasis is a hereditary skin disease and there is no way to prevent it.To prevent worsening symptoms, moisturizing the skin and managing the indoor environment are useful.Avoid prolonged bathing, be careful not to rub your skin too much, and minimize the use of soap.After bathing, a moisturizer is applied to prevent the skin from drying out.Indoor air conditioners and humidifiers are used to maintain proper temperature and humidity.Be careful because your body temperature tends to rise in summer.