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hypopituitary disease

LemonDKel 2022. 7. 31. 03:51
Overview
The pituitary gland is an endocrine organ in the skull that secretes various hormones and controls the human body.Pituitary dysfunction is caused by a decrease in the secretion of one kind or a plurality of hormones secreted by the pituitary gland.Among the eight hormones secreted by the pituitary gland, six are related to each other: adrenal cortical stimulating hormone, thyroid stimulating hormone, growth hormone, luteinizing hormone, follicular stimulating hormone, and prolactin.cause
Pituitary tumors are the most common causes of pituitary dysfunction, and other causes include specific inflammatory diseases and a decrease in blood flow to the pituitary gland.Although the pituitary tumor itself is often benign, it causes hypothyroidism by compressing the normal pituitary gland.In addition to surgery for pituitary adenoma and radiation exposure, the function of the pituitary gland may deteriorate due to trauma.In addition to the pituitary gland, diseases around the pituitary gland such as cranopharyngeal tumor and ratke cyst also cause the secretion of hormones to decrease.If the cause is unclear, it is thought that some kind of immunological abnormality may be involved.Most of them have nothing to do with heredity, but it is possible that genetic abnormalities related to the pituitary gland may be affecting people who are related to the same disease.symptom
If a large pituitary tumor is the cause, the visual field and vision will be impaired.Other symptoms vary depending on the type of pituitary hormone in which secretion is decreasing.The most serious is decreased secretion of adrenal cortical stimulating hormone, which leads to adrenal insufficiency.Symptoms such as anorexia, weight loss, and severe fatigue can be fatal.In addition, insufficient thyroid-stimulating hormones can cause coldness, weight gain, and dry skin.When growth hormone secretion decreases, the child′s growth condition deteriorates, and adults experience symptoms such as increased body fat and muscle weakness.Luteinizing hormone and follicle stimulating hormone are hormones related to gonadal development and sexual desire, and when they decrease, they cause amenorrhea and infertility in women, as well as decreased sexual desire and erection disorders in men.Prolactin is a hormone that affects the production of breast milk, and when it decreases, the amount of breast milk decreases or stops coming out.examination and diagnosis
A blood test is conducted to determine the blood concentration of various hormones and to determine which hormone secretion is decreasing.In addition, urine tests may be performed to measure hormones in urine, or multiple load tests may be required.In order to specify the cause of the hypothyroidism, CT and MRI images are examined.If a tumor such as pituitary adenoma is seen, the spread of the tumor is also confirmed.Furthermore, considering the possibility that the lesion is spreading beyond the pituitary gland, various tests are conducted including the evaluation of arrhythmia by electrocardiogram, swelling of lymph nodes by chest X-ray, and the examination of grape membrane inflammation by fundus examination.treatment
Mainly deficient hormones are supplemented with synthetic hormones.If the adrenal cortical hormone is lowered, the adrenal cortical hormone is supplemented, and if the secretion of the thyroid stimulating hormone is lowered, the thyroid hormone is taken internally.These two hormones are essential for life activities regardless of age or gender.In addition, growth hormones affect not only height growth but also muscles and fat, so if there is a shortage, a treatment to replenish growth hormones is provided.As for the reduction of the luteinizing hormone and follicle stimulating hormone, the sex hormone is supplemented by an injection.These hormone replacement treatments often help people recover to a degree that does not interfere with their daily lives.In the case of pituitary adenoma, surgery is performed.Surgery is often done through the nose, depending on the size of the tumor.Radiation and chemotherapy may be selected depending on the symptoms.